Balıkesir is a city located in the Marmara region of Turkey. Here are the directions to Balıkesir from Istanbul, the largest city in Turkey: By car: Take the O-3/E80 highway from Istanbul towards the west, following the signs for Edirne. Continue on the O-3/E80 highway for approximately 150 kilometers (about 2 hours). Take the exit for Balıkesir, following the signs for the city center. Follow the signs to your destination in Balıkesir. By bus: Many bus companies offer regular service from Istanbul to Balıkesir, including Metro Turizm, Kamil Koç, and Ulusoy. Buses depart from several bus stations in Istanbul, including Esenler Otogar and Harem Otogar. The journey by bus takes approximately 4-5 hours, depending on traffic and the route taken. By train: Balıkesir is also accessible by train from Istanbul, with regular service provided by Turkish State Railways. Trains depart from Istanbul's Halkalı Train Station and arrive at Balıkesir Train Station. The journey by train takes approximately 6-7 hours, depending on the train schedule and route. These are the main options for traveling from Istanbul to Balıkesir. The exact travel time and route may vary depending on your mode of transportation and the traffic conditions.